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pentobarbital will lessen the level or effect of nilotinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.pentobarbital will decrease the level or influence of rabeprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Not known.buprenorphine subdermal implant and pentobarbital bo